Karpuzlu is a district of Aydin City in the Aegean region of Turkey, 56 km. to Aydin City Center.
Karpuzlu's reached by turning off the road from Aydin to Cine. There's infrequent public transport from both towns to Karpuzlu, which can also be reached by the mountain road from Milas. This latter route is popular with tourists on "jeep safaris" coming to see the ruins of Alinda.
The town is partially situated on the slopes of a hill on the top of which can be seen the well preserved ruins of the ancient acropolis of Alinda.
The modern district of Karpuzlu covers part of the Cine plain that is part of the southern reaches of the fertile Menderes River valley. The main crops are cotton, corn and many other grains and vegetables.